Caenorhabditis elegans

Nuclear cGMP-Dependent Kinase Regulates Gene Expression via Activity-Dependent Recruitment of a Conserved Histone Deacetylase Complex

Genetics / Caenorhabditis elegans / Reproduction / Gene expression / Male Reproduction Health / Mutation / Female / Animals / HIstone Deacetylase / Genetic Screening / Physiological Response / Egg Laying / Cell nucleus / Foraging Behavior / PLoS Genetics / Proteome analysis / Protein Kinase / Protein Binding / Second Messengers / Gene Expression Regulation / Gene expression profiling / Histone deacetylases / Mutation / Female / Animals / HIstone Deacetylase / Genetic Screening / Physiological Response / Egg Laying / Cell nucleus / Foraging Behavior / PLoS Genetics / Proteome analysis / Protein Kinase / Protein Binding / Second Messengers / Gene Expression Regulation / Gene expression profiling / Histone deacetylases

A tension-induced mechanotransduction pathway promotes epithelial morphogenesis

Caenorhabditis elegans / Cell Migration / Wound Healing / Morphogenesis / Multidisciplinary / Nature / Signal Transduction / Cellular mechanotransduction / Animals / Muscles / Phosphorylation / Intermediate Filaments / Epidermis / Phenotype / Muscle contraction / Resistance Genes Mechanism) / Conformational Change / Nature / Signal Transduction / Cellular mechanotransduction / Animals / Muscles / Phosphorylation / Intermediate Filaments / Epidermis / Phenotype / Muscle contraction / Resistance Genes Mechanism) / Conformational Change

Environmental predators as models for bacterial pathogenesis

Microbiology / Environmental microbiology / Caenorhabditis elegans / Drosophila melanogaster / Humans / Animals / Gram Positive Bacteria / Gram-negative bacteria / Bacterial infections / Predatory Behavior / Environmental / Amoeba / Animals / Gram Positive Bacteria / Gram-negative bacteria / Bacterial infections / Predatory Behavior / Environmental / Amoeba

Classical genetics goes high-tech

Genetics / Technology / Caenorhabditis elegans / Biological Sciences / Automation / Genetic Testing / Mutation / Animals / Genetic Testing / Mutation / Animals

Novel fungicidal benzylsulfanyl-phenylguanidines

Organic Chemistry / Caenorhabditis elegans / Biofilm / Animals / Sulfides / Bacteria / Candida albicans / Staphylococcus epidermidis / Antifungal Agents / Biological activity / Guanidines / Chemical Synthesis / Bactericidal Activity / Molecular Structure / Minimal Bactericidal Concentration / Bacteria / Candida albicans / Staphylococcus epidermidis / Antifungal Agents / Biological activity / Guanidines / Chemical Synthesis / Bactericidal Activity / Molecular Structure / Minimal Bactericidal Concentration

Novel fungicidal benzylsulfanyl-phenylguanidines

Organic Chemistry / Caenorhabditis elegans / Biofilm / Animals / Sulfides / Bacteria / Candida albicans / Staphylococcus epidermidis / Antifungal Agents / Biological activity / Guanidines / Chemical Synthesis / Bactericidal Activity / Molecular Structure / Minimal Bactericidal Concentration / Bacteria / Candida albicans / Staphylococcus epidermidis / Antifungal Agents / Biological activity / Guanidines / Chemical Synthesis / Bactericidal Activity / Molecular Structure / Minimal Bactericidal Concentration

C. elegans: a novel pharmacogenetic model to study Parkinson\'s disease

Genetics / Cognitive Science / Caenorhabditis elegans / Molecular Mechanics / Protein-Protein Interaction / Tissue culture / Clinical Sciences / Dopamine Transporter / Model System / Degeneration / Genetic Analysis / Metabolic pathway / Drug Targeting / Substantia nigra pars compacta (SNpc) / Tissue culture / Clinical Sciences / Dopamine Transporter / Model System / Degeneration / Genetic Analysis / Metabolic pathway / Drug Targeting / Substantia nigra pars compacta (SNpc)

acr-23 Encodes a Monepantel-Sensitive Channel in Caenorhabditis elegans

Microbiology / Immunology / Caenorhabditis elegans / Medical Microbiology / Ion Channels / Mutation / Animals / Drug Resistance / Xenopus laevis / Aminoacetonitrile / Gene Expression Regulation / Mutation / Animals / Drug Resistance / Xenopus laevis / Aminoacetonitrile / Gene Expression Regulation

Computational identification of operon-like transcriptional loci in eukaryotes

Caenorhabditis elegans / Drosophila melanogaster / Transcriptome / Animals

Pan-phylum Comparison of Nematode Metabolic Potential

Caenorhabditis elegans / Transcriptome / Biological Sciences / Phylogeny / Humans / Female / Animals / Male / Gene Regulatory Networks / Nematoda / Species Specificity / Proteome / Metabolome / Female / Animals / Male / Gene Regulatory Networks / Nematoda / Species Specificity / Proteome / Metabolome

Glutaredoxin deficiency exacerbates neurodegeneration in C. elegans models of Parkinson\'s disease

Caenorhabditis elegans / Molecular Evolution / Oxidative Stress / Alpha Synuclein / Biological Sciences / Humans / Animals / Human Molecular Genetics / Phenotype / Homeostasis / Cysteine / Cell Survival / Dopaminergic Neurons / Parkinson Disease / Gene Expression Regulation / Humans / Animals / Human Molecular Genetics / Phenotype / Homeostasis / Cysteine / Cell Survival / Dopaminergic Neurons / Parkinson Disease / Gene Expression Regulation

Chemical genetics identifies Rab geranylgeranyl transferase as an apoptotic target of farnesyl transferase inhibitors

Genetics / Caenorhabditis elegans / Enzyme Inhibitors / Apoptosis / Gene expression / Caspases / RNA interference / Humans / Germ Cells / Mutagenesis / Animals / Neoplasms / Cancer Cell / Calcium Binding Proteins / Antineoplastic Agents / Neurosciences / Caspases / RNA interference / Humans / Germ Cells / Mutagenesis / Animals / Neoplasms / Cancer Cell / Calcium Binding Proteins / Antineoplastic Agents / Neurosciences

A Target Repurposing Approach Identifies N-myristoyltransferase as a New Candidate Drug Target in Filarial Nematodes

Caenorhabditis elegans / Computational Biology / Biological Sciences / Animals / Drug Delivery Systems / Molecular Targeted Therapy

Importin α: a multipurpose nuclear-transport receptor

Caenorhabditis elegans / Biological Sciences / Drosophila / Phylogeny / Cell Differentiation / Humans / Animals / Cell nucleus / Protein Conformation / Cytoplasm / Dimerization / Humans / Animals / Cell nucleus / Protein Conformation / Cytoplasm / Dimerization

Squeezing an egg into a worm: C. elegans embryonic morphogenesis

Caenorhabditis elegans / Morphogenesis / Animals

Quality Control Compartments Coming of Age

Caenorhabditis elegans / Aging / Drosophila melanogaster / Quality Control / Neurodegenerative Diseases / Brain / Humans / Animals / Protein Aggregation / Peptides / Traffic / Degradation / Proteins / Neurons / Rats / Biochemistry and cell biology / Brain / Humans / Animals / Protein Aggregation / Peptides / Traffic / Degradation / Proteins / Neurons / Rats / Biochemistry and cell biology

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